Radiesse™ is a safe, FDA-approved dermal filler that has been used in hundreds of thousands of patients to achieve a natural, youthful appearance. It is especially useful to restore volume to the cheeks and to soften deepened nasolabial folds. Radiesse™ is composed of tiny calcium-based microspheres suspended in a natural gel. The microspheres support and stimulate the growth of your own collagen they gradually break down over time. Radiesse™ typically lasts a year or more.